Patho-physiological studies on the Reverse Effect of Curcumin (Curcuma longa, Zingiberaceae) and Ursofalk (Ursodeoxycholic acid) against the Toxicity of Carbon Tetrachloride on Albino Rats
نویسنده
چکیده
Carbon tetrachloride (CC14) is considered as one of the environmental pollutants which mainly caused hepatotoxic effect; it is most widely used for experimental induction of hepatic cirrhosis [1] CCl4 induces liver necrosis, fibrosis, cirrhosis and acute tubular necrosis in the kidney [2] In addition, CCl4 also alters the antioxidant profile of the liver including the antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GSH) [3]. Thus, CCl4 was chosen in this study as model for investigating radical-induced damage and its prevention in albino rats.
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تاریخ انتشار 2016